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Assist Prof Dr. Jiyeon Han | Bioinorganic chemistry | Best Researcher Award

 Professor at University of Seoul , South Korea

Dr. Jiyeon Han is an Assistant Professor in the Department of Applied Chemistry at the University of Seoul. Her research delves into the intricate roles of metals, amyloid-β, and neuropeptides in Alzheimer’s Disease, leveraging both molecular-level studies and chemical tool development to explore and address neurodegenerative processes.

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Dr. Han has a substantial publication record with 25 articles to her name, including notable journals like Nature Chemistry, Accounts of Chemical Research, and Proceedings of the National Academy of Sciences. Her work has earned several front cover features and high-impact citations.

Education

Dr. Han earned her B.S. and M.S. from Ulsan National Institute of Science and Technology (UNIST), followed by her Ph.D. and postdoctoral training at Korea Advanced Institute of Science and Technology (KAIST) under Professor Mi Hee Lim.

Research Focus

Her primary research focuses on the molecular interactions of metals and amyloid-β in Alzheimer’s Disease, including the development of novel chemical tools to target and analyze pathogenic elements and the mechanisms of metal-induced neurodegeneration.

Professional Journey

Dr. Han transitioned from a postdoctoral scholar at KAIST to her current role at the University of Seoul in September 2022. Her career trajectory highlights her commitment to advancing the field of bioinorganic chemistry and neurodegenerative disease research.

Honors & Awards

She has received several prestigious awards, including the S-Oil Best Ph.D. Thesis Award, the 2022 Future Talent Award, and the Best Ph.D. Thesis Award from the Korean Chemical Society, recognizing her exceptional contributions to the field.

Publications Noted & Contributions

Her notable publications include studies on copper trafficking systems, the impact of metal ions on amyloid-β, and mechanistic insights into Alzheimer’s Disease. Her work has been highlighted in prominent journals and featured on front covers.

Research Timeline

Dr. Han’s research timeline includes significant milestones such as her postdoctoral fellowship in 2022, the receipt of various awards throughout 2022 and 2023, and her ongoing contributions to bioinorganic chemistry through her current faculty position.

Collaborations and Projects

Her collaborative projects span across various institutions and involve extensive work with KAIST, UNIST, and other Korean universities, focusing on metal ion interactions, chemical tool development, and neurodegenerative disease mechanisms.

 

Publications

  1. Colorimetric Detection of Fe3+ and Fe2+ and Sequential Fluorescent Detection of Al3+ and Pyrophosphate by an Imidazole-Based Chemosensor in a Near-Perfect Aqueous Solution
    TG Jo, KH Bok, J Han, MH Lim, C Kim
    Dyes and Pigments 139, 136-147 (2017)
    Cited by: 96
  2. Regulatory Activities of Dopamine and Its Derivatives Toward Metal-Free and Metal-Induced Amyloid-β Aggregation, Oxidative Stress, and Inflammation in Alzheimer’s Disease
    E Nam, JS Derrick, S Lee, J Kang, J Han, SJC Lee, SW Chung, MH Lim
    ACS Chemical Neuroscience 9 (11), 2655-2666 (2018)
    Cited by: 84
  3. Structure-Mechanism-Based Engineering of Chemical Regulators Targeting Distinct Pathological Factors in Alzheimer’s Disease
    MW Beck, JS Derrick, RA Kerr, SB Oh, WJ Cho, SJC Lee, Y Ji, J Han, …
    Nature Communications 7 (1), 13115 (2016)
    Cited by: 83
  4. Link of Impaired Metal Ion Homeostasis to Mitochondrial Dysfunction in Neurons
    E Nam, J Han, JM Suh, Y Yi, MH Lim
    Current Opinion in Chemical Biology 43, 8-14 (2018)
    Cited by: 72
  5. A Novel “Off-On” Type Fluorescent Chemosensor for Detection of Zn2+ and Its Zinc Complex for “On-Off” Fluorescent Sensing of Sulfide in Aqueous Solution, In Vitro and In Vivo
    JM Jung, JH Kang, J Han, H Lee, MH Lim, KT Kim, C Kim
    Sensors and Actuators B: Chemical 267, 58-69 (2018)
    Cited by: 63

Strength for Best Researcher Award

      1. High-Impact Publications
        Dr. Han’s research has been featured in top-tier journals like Nature Communications and ACS Chemical Neuroscience, demonstrating significant contributions to the field of bioinorganic chemistry and neurodegenerative diseases.
      2. Innovative Research Focus
        Her work on the molecular roles of metals and amyloid-β in Alzheimer’s Disease showcases a novel approach to understanding and targeting neurodegenerative processes.
      3. Awards and Recognition
        Dr. Han has received several prestigious awards, including the S-Oil Best Ph.D. Thesis Award and the Best Ph.D. Thesis Award from the Korean Chemical Society, underscoring her excellence in research.
      4. Collaborative Efforts
        Her extensive collaborations with institutions like KAIST and UNIST highlight her ability to work across different research environments, enhancing the impact and reach of her studies.
      5. Substantial Citations
        Her key publications have been highly cited, reflecting the broad recognition and influence of her research in the academic community.

      Areas for Improvement

      1. Broader Research Topics
        Expanding research to include a wider range of neurodegenerative diseases could enhance the applicability of her findings.
      2. Interdisciplinary Approaches
        Integrating insights from other fields such as computational biology or systems biology might provide a more comprehensive understanding of Alzheimer’s Disease mechanisms.
      3. Increased Funding Opportunities
        Securing additional funding could support larger-scale studies and the development of new chemical tools.
      4. Enhanced Public Engagement
        Greater efforts in communicating her research to the public and engaging in outreach activities could increase awareness of her work and its implications.
      5. Long-Term Research Impact
        Focusing on longitudinal studies could help track the long-term effects of her research findings on Alzheimer’s Disease and related areas.

      Conclusion

      Dr. Jiyeon Han’s achievements as an assistant professor in the Department of Applied Chemistry at the University of Seoul are marked by her groundbreaking research on the roles of metals and amyloid-β in Alzheimer’s Disease. Her high-impact publications, prestigious awards, and successful collaborations underscore her contributions to bioinorganic chemistry. However, there are opportunities for growth in expanding research topics, employing interdisciplinary approaches, securing more funding, enhancing public engagement, and focusing on long-term research impact. Addressing these areas could further elevate her research profile and broader influence in the scientific community.

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Jiyeon Han | Matrix composites | Best Researcher Award

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